Table 5 Examples of translational research support at NIH
From: White paper on microbial anti-cancer therapy and prevention
| Program | Mission/Objective | Website link |
|---|---|---|
| NCI: Experimental Therapeutics (NExT) Program | Supports promising new anticancer-drug (small molecule, biologics) discovery and development projects towards clinical evaluation and registration. | https://next.cancer.gov/ |
| NCI: Division of Cancer Prevention (PREVENT) | Supports development in cancer prevention intervention and biomarkers. | https://prevention.cancer.gov/major-programs/prevent-cancerpreclinical |
| NCATS: Bridging Interventional Development Gaps (BrIDGs) Program | Advances promising therapeutic agents for both common and rare diseases through late-stage preclinical development toward an IND application. | https://ncats.nih.gov/bridgs |
| NCATS: Therapeutics for Rare and Neglected Diseases (TRND) Program | Supports preclinical development of therapeutic drugs to treat rare and neglected disorders toward the goal of an IND application. | https://ncats.nih.gov/trnd |
| NIAID: Translation Resource Tools | Supports preclinical and clinical research for vaccines, diagnostics, and therapeutics. | https://www.niaid.nih.gov/research/therapeutic-developmentservices |
| NINDS: Create Bio Program | Supports optimization of biotechnology product and biologics-based therapies for development and IND-enabling studies, as well as early-phase clinical trials. | https://www.ninds.nih.gov/Current-Research/Research-Funded-NINDS/Translational-Research/CREATE-BIO |
| NHLBI: SMARTT Program | Accelerates translation of research for therapeutic candidates or diagnostic imaging agents from in vivo efficacy to IND submission for treatment of heart, lung, or blood diseases. | https://www.nhlbismartt.org/ |