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Table 1 Putative HLA class I mCALR neoepitopes

From: Isolation of T cell receptors targeting recurrent neoantigens in hematological malignancies

Neoepitope Peptide Predicted HLA Restriction Predicted HLA binding affinity (nM)
RPRTSCREA CALR-REA HLA-B*07:02 12
SPARPRTSC CALR-SPA HLA-B*07:02 22
RMRRTRRKM CALR-RMR HLA-B*07:02 56
RPRTSCREAC CALR-REAC HLA-B*07:02 23
RMMRTKMRMR CALRp2 HLA-A*03:01 41
KMRMRRMRR CALRp7 HLA-A*03:01 35
RTRRKMRRK CALRp15 HLA-A*03:01 54
  1. NetMHC was used to identify neoepitopes derived from the 36 amino acid mCALR C terminus that are predicted to bind strongly (< 500 nM) to common European Caucasoid HLA class I alleles