Fig. 2
From: Sick sinus syndrome associated with anti-programmed cell death-1
Serial vital signs and hormone levels following anti-PD-1 treatment. Heart rate (HR) and systolic blood pressure (SBP) dropped after six cycles of pembrolizumab (P) treatment. Cortisol and adrenocorticotropic hormone (ACTH) levels declined, but thyroid-stimulating hormone (TSH) and free T4 (fT4) remained within a normal range. HR and SBP were reversed after prescription of cortisone. Cortisol and ACTH levels returned to a normal range about one month later