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Table 2 Multivariate proportional hazard ratios

From: Association between pretreatment lymphocyte count and response to PD1 inhibitors in head and neck squamous cell carcinomas

Parameter

Hazard Ratio

Lower 95%

Upper 95%

P value

Primary Cohort

 ALC < 600 vs. ≥600

3.65

1.05

12.98

0.04

 L% < 9 vs. ≥9

9.68

2.91

37.62

0.0002

 NLR ≥7 vs. < 7

14.74

4.14

63.96

< 0.0001

Expanded Cohort

 ALC < 600 vs. ≥600

4.89

1.90

12.90

0.001

 L% < 9 vs. ≥9

5.55

2.13

15.72

0.0004

 NLR ≥7 vs. < 7

4.69

1.99

11.72

0.0004

  1. Multivariate analyses were adjusted for the following independent variables: age, gender, race, smoking history, primary site of cancer, viral association, ECOG performance status, number of prior lines of therapy, and immunotherapy regimen; ALC Absolute lymphocyte count, L% Lymphocyte %, NLR Neutrophil-lymphocyte ratio