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Fig. 3 | Journal for ImmunoTherapy of Cancer

Fig. 3

From: Fatal enteric plexus neuropathy after one dose of ipilimumab plus nivolumab: a case report

Fig. 3

C4d immunoreactivity around ganglia and nerves. a Intense C4d immunolabelling is observed around an aneuronal ganglion (g) and in the location of small intramuscular nerves (arrows) in the colon of the patient. b In contrast, no significant C4d expression is observed in ganglia (g) in the colon from a cadaveric control patient with no history of ipilimumab or novilumab exposure or dysmotility. v, blood vessel. Scale bars = 100 μm

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