Fig. 3

Response of pulmonary inflammatory lesions to immune suppressive therapy. a CT-scan at the time point when the inflammatory lesions were first detected after 2 years of pembrolizumab therapy. b Initial response to corticosteroid therapy (1 mg/kg prednisone). Pulmonary inflammatory lesions were clearly regressing after initial therapy. c CT-scan acquired during immune suppression with mycophenolate and after tapering of prednisone (before start infliximab). d CT-scan after 6 months of infliximab therapy. No inflammatory lesions can be observed anymore. e ¹⁸FDG-PET-CT scan after the infliximab therapy was stopped. A durable remission in terms of the melanoma and the pneumopathy was found