Fig. 3
From: Fluorine-19 MRI for detection and quantification of immune cell therapy for cancer
PBMC 19F MRI imaging in immunocompromized mice and phantoms. a In vivo composite 1H/19F MRI image of PFPE-labeled human PBMC following subcutaneous flank injection of 6 × 106 cells (blue arrow) in nude mouse. For preliminary clinical MRI protocol implementation, PFPE-labeled PBMC were injected intradermally and intramuscularly in a ham shank phantom. b Intradermal injection alone consisted of 20 × 106 cells (yellow arrow). c Composite images of shanks receiving both intradermal and intramuscular PBMC injections of 4.5 × 106 cells each. R indicate references used for quantification. (Adapted from Reference [61])