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Fig. 4 | Journal for ImmunoTherapy of Cancer

Fig. 4

From: Fluorine-19 MRI for detection and quantification of immune cell therapy for cancer

Fig. 4

Indirect visualization of T cell therapy efficacy via cancer cell oximetry. a Composite 19F and 1H image of PCE labeled glioma (GL261) cells in the right striatum 5 days after tumor inoculation in C57BL/6 mice. A diluted PCE reference capillary is placed below the animal (bottom). b In vivo longitudinal tumor pO2 measurement after Pmel-1 mouse derived CD8+ T cell, wild-type T cell injection or no treatment. Transient hyperoxia is observed with administration of Pmel-1 CD8+ T cells. (Adapted from Reference [71])

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