Table 1 Patient demographics
Patient | Skeletal AE | Age | Sex | Race | BMI | Tumor type and stage | Treatment Regimen | Bone Metastases? | Other irAEs |
|---|---|---|---|---|---|---|---|---|---|
1 | Compression fractures of T6, T7, T10, T11, and T12; rib and pelvic fractures | 75 | M | C | 19 | Melanoma Stage IV | Pembrolizumab | No | None |
2 | Compression fractures, T6–12, L1 | 52 | M | C | 27 | Melanoma Stage IV | Nivolumab | Yes | None |
3 | Compression fracture, T11; lumbar osteomalacia | 58 | M | C | 29 | Melanoma Stage IV | Pembrolizumab | No | None |
4 | Resorptive bone lesion, left shoulder | 60 | M | C | 24 | Melanoma Stage IV | Ipilimumab/nivolumab | No | Pneumonitis, hypophysitis, inflammatory arthritis |
5 | Resorptive bone lesion, right wrist | 60 | F | C | 26 | Renal cell carcinoma Stage IV | Nivolumab | Yes | Inflammatory arthritis |
6 | Resorptive bone lesion, right clavicle | 51 | M | C | 25 | Non small cell lung cancer Stage II | Ipilimumab/nivolumab | Yes | Inflammatory arthritis |