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Table 1 Baseline demographic and clinical characteristics of treated patients

From: Safety and efficacy of nivolumab in combination with sunitinib or pazopanib in advanced or metastatic renal cell carcinoma: the CheckMate 016 study

Characteristic

N + S (N = 33)

N + P (N = 20)

Age, years

 Median (range)

57.0 (38–75)

56.0 (40–72)

Age <65 years, n (%)

24 (72.7)

17 (85.0)

Sex, n (%)

 Male

26 (78.8)

18 (90.0)

 Female

7 (21.2)

2 (10.0)

Race, n (%)

 Caucasian

28 (84.8)

18 (90.0)

 Asian

1 (3.0)

0

 Black/African American

2 (6.1)

1 (5.0)

 Other

2 (6.1)

1 (5.0)

Ethnicity, n (%)

 Hispanic/Latino

2 (6.1)

0

 Not Hispanic/Latino

29 (87.9)

18 (90.0)

 Not reported

2 (6.1)

2 (10.0)

MSKCC risk category, n (%)

 Favorable

16 (48.5)

4 (20.0)

 Intermediate

16 (48.5)

14 (70.0)

 Poor

1 (3.0)

2 (10.0)

Prior surgery, n (%)

33 (100.0)

20 (100.0)

Prior radiotherapy, n (%)

5 (15.2)

10 (50.0)

Prior systemic therapy, n (%)

14 (42.4)

20 (100.0)

 VEGFR inhibitor

5 (15.2)

17 (85.0)

 Other antiangiogenic

7 (21.2)

17 (85.0)

 Cytokine

9 (27.3)

10 (50.0)

 mTOR inhibitor

0

3 (15.0)

 Other

3 (9.1)

4 (20.0)

No. of prior therapies, n (%)

 0

19 (57.6)

0

 1

14 (42.4)

14 (70.0)

 2

0

4 (20.0)

 3

0

1 (5.0)

  ≥4

0

1 (5.0)

Treatment setting, a n (%)

 Adjuvant

3 (9.1)

4 (20.0)

 Metastatic

0

2 (10.0)

 Neoadjuvant

11 (33.3)

16 (80.0)

  1. aMore than one setting per patient may be reflected in the frequency