Fig. 1

Hypothetical example of a spider plot showing tumor growth or shrinkage from baseline in a cohort of patients. Patients are often color coded to correspond to their best objective response. By displaying index lesion tumor burden over time, spider plots clearly illustrate tumor burden changes over time. They can demonstrate a favorable antitumor response in index lesions by showing their decrease, even in patients determined to have a best response of progressive disease as defined by the presence of a new lesion