Fig. 2

Hypothetical example of a swimmer plot showing time of objective response in relationship to duration of treatment and time of treatment cessation. Symbols along each bar and at the end of each bar could be used to represent various relevant clinical events, such as disease progression or start of a new anticancer therapy. Swimmer plots provide useful information about responses, which may start after cessation of immunotherapy, and about the potential persistence of these responses even without ongoing treatment. Continuation of response despite immunotherapy discontinuation is an important efficacy metric