Table 4 Response rate (RR) by radiologic (preoperative; 6 weeks from baseline) and histologic (6–8 weeks from baseline) assessments
All patients (N = 28) | Ipi 3 mg/kg (n = 14) | Ipi 10 mg/kg (n = 14) | ||||
|---|---|---|---|---|---|---|
No. pts. | % | No. pts. | % | No. pts. | % | |
Radiologic preoperative RR (WHO; unconfirmed) | 10 (9 PR, 1CR) | 36% | 4 (3 PR, 1 CR) | 29 | 6 (All PR) | 43 |
Pathologic complete RR (no viable tumor on histologic assessment) | 9 | 32% | 5 | 36 | 4 | 29 |
Among radiologic responders | ||||||
• One relapsed and later responded to anti-PD1 antibody therapy | ||||||
Among complete pathologic responders | ||||||
• None relapsed to date | ||||||