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Table 1 Patient demographics and baseline clinical characteristics by dose level
| Characteristic | 2 mg/kg (n = 10) | 3 mg/kg (n = 20) |
|---|---|---|
| Median age, y (range) | 69 (23–83) | 65 (22–81) |
| Male, n (%) | 8 (80) | 10 (50) |
| White, n (%) | 8 (80) | 20 (100) |
| ECOG performance status, n (%) | ||
| 0 | 4 (40) | 3 (15) |
| 1 | 6 (60) | 15 (75) |
| 2 | 2 (10) | |
| Disease stage, n (%) | ||
| I | 0 | 2 (10) |
| II | 1 (10) | 3 (15) |
| III | 4 (40) | 3 (15) |
| IV | 5 (50) | 12 (60) |
| Prior treatment with radiation therapy, n (%) | 3 (30) | 6 (30) |
| Prior treatment with systemic therapy, n (%) | 10 (100) | 20 (100) |
| Median number of prior regimens (range) | 4.5 (1–8) | 3.5 (1–9) |
| Prior treatment with surgery, n (%) | 3 (30) | 3 (15) |
| History of cancer(s) other than current cancer, n (%) | 5 (50) | 3 (15) |
