Fig. 1

Evolution of pulmonary, mediastinal and vertebral lesions seen in ¹⁸F-FDG PET/CT’s MIP images during treatment with anti-PD1. MIP images (front and lateral view) from different ¹⁸F-FDG PET/CT’s. a Multiple FDG avid lesions in the lungs, mediastinum and thoracic vertebral bodies. b Metabolic resolution of the metastatic lung and mediastinal lesions, however there is increased FDG uptake in previous thoracic bone lesions associated with new hypermetabolic bone lesion (arrowhead). c Metabolic resolution of most thoracic bone lesions, consistent with partial metabolic response (PMR)