Fig. 4From: Activity of durvalumab plus olaparib in metastatic castration-resistant prostate cancer in men with and without DNA damage repair mutationsGenomic Alterations. Presence or absence of alterations in DDR and other significant genes. Genomic data are from OncoVar sequencing, a capture-based sequencing panel of 500 cancer-associated genes. Copy number calls are based on read depth and minor allele frequency in the OncoVar sequencing results. All patients had germline sequencing performed. As indicated, 3 patients had insufficient tumor tissue on biopsy and no archival tissue availableBack to article page