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Table 1 Baseline characteristics (n = 17)

From: Activity of durvalumab plus olaparib in metastatic castration-resistant prostate cancer in men with and without DNA damage repair mutations

Baseline characteristics

n (% or range)

Age

66 (45–79)

Baseline PSA (ng/mL)

79.7 (3.9–2356)

Baseline Hemoglobin (g/dL)

12.2 (9.3–14.5)

Baseline LDH (U/L)

241 (153–351)

Baseline Alkaline Phosphatase (U/L)

80 (56–643)

Baseline CTCs (in 10 mL blood)

12 (0–2107)

Prior treatment with:

 Enzalutamide

16 (94%)

 Abiraterone

11 (65%)

 Both

10 (59%)

 Prior immunotherapy

8 (47%)

 Prior chemotherapy

11 (65%)

Gleason score

 <  8

5 (29%)

 8–10

12 (71%)

ECOG performance status

 0

2 (12%)

 1

14 (82%)

 2

1 (6%)

Disease site:

 Bone only

5 (29%)

 Bone/soft tissue/viscera

12 (71%)