Skip to main content
Fig. 5 | Journal for ImmunoTherapy of Cancer

Fig. 5

From: 1-Pyrroline-5-carboxylate released by prostate Cancer cell inhibit T cell proliferation and function by targeting SHP1/cytochrome c oxidoreductase/ROS Axis

Fig. 5

Difference in Metabolites and PRODH Expression Between PCC and Normal Cell. (a) All identified and analyzed different metabolites between LNCaP and HK-2 cell. The content of P5C (red marked) in LNCaP cultured media obviously exceeded the content in HK-2. (b) All identified and analyzed different metabolites between PC3 and HK-2 cell. The content of P5C (red marked) in PC3 cultured media obviously exceeded the content in HK-2. (c-d) The mRNA and protein expression of PRODH in four cell lines. (e) The expression of PRODH in PCa and BPH tissue. Columns are expressed as mean ± SD. ** P < 0.05; ***P < 0.01. (f) The expression of PRODH in PCa and BPH tissues by immunohistochemical

Back to article page