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Fig. 3 | Journal for ImmunoTherapy of Cancer

Fig. 3

From: Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients

Fig. 3

Relationship between C3M/PRO-C3 ratio at baseline and clinical outcome. C3M/PRO-C3 serum levels were dichotomized by the 25th percentile dividing the patients into a group with low C3M/PRO-C3 (Q1) and high C3M/PRO-C3 (Q2 + Q3 + Q4). a Quantity of patients achieving disease control (CR + PR + SD) compared to non-responders (PD) in each group. b Kaplan-Meier survival curve illustrate the overall survival for the two groups. A log-rank test was used to determine differences between the survival curves where a p-value of p < 0.05 was considered statistically significant

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