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Table 1 PD-L1 IHC and RNA-seq results for 209 samples

From: Next generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors

Test Result Test RCC Melanoma NSCLC
≥1% TPS IHC 5 (11%) 19 (25%) 38 (43%)
< 1% TPS IHC 40 (89%) 57 (75%) 50 (57%)
≥50% TPS IHC NA NA 19 (22%)
< 50% TPS IHC NA NA 69 (78%)
≥1% ICS IHC 4 (9%) NA NA
< 1% ICS IHC 41 (91%) NA NA
> 75 rank (high) RNA-seq 9 (20%) 11 (14%) 35 (40%)
25–75 rank (moderate) RNA-seq 24 (53%) 39 (51%) 42 (48%)
> 25 rank (low) RNA-seq 12 (27%) 26 (35%) 11 (12%)
  Total 45 76 88