Prognostic value of CD8 + PD-1+ immune infiltrates and PDCD1 gene expression in triple negative breast cancer

Table 1 Multivariate analysis of PD-1⁺ immune infiltrates and PD-L1 tumor cells with survival outcomes in patients with TNBC. Analysis was adjusted for tumor size, grade, age and lymph node status

Biomarkers	HR	95% CI	P-value
OS
PD-1⁺ immune infiltrates High vs. low	0.61	0.33–1.13	0.110
PD-1⁺ immune infiltrates (every 1 cell increment)	0.96	0.91–1.01	0.080
PD-L1 expression High vs. low	0.40	0.18–0.86	0.020*
DFS
PD-1⁺ immune infiltrates High vs. low	0.48	0.29–0.81	0.005*
PD-1⁺ immune infiltrates (every 1 cell increment)	0.95	0.93–1.00	0.030*
PD-L1 expression High vs. low	0.39	0.20–0.76	0.006*