Skip to main content

Table 3 Multivariate analysis of PDCD1, CD274, IFNG and IFN signaling genes RNA expression survival outcomes in patients with TNBC. Analysis was adjusted for tumor size, grade, age and lymph node status

From: Prognostic value of CD8 + PD-1+ immune infiltrates and PDCD1 gene expression in triple negative breast cancer

Biomarkers HR 95% CI P-value
OS
PDCD1 expression (every 1 unit increment) 0.02 0.00–0.36 0.007*
CD274 expression (every 1 unit increment) 0.12 0.02–0.81 0.030*
IFNG expression
 High vs. low
0.38 0.21–0.72 0.003*
 Interferon signaling gene expression
 High vs. low
0.59 0.29–1.17 0.132
DFS
PDCD1 expression (every 1 unit increment) 0.08 0.01–0.83 0.034*
CD274 expression (every 1 unit increment) 0.19 0.04–0.97 0.045*
IFNG expression
 High vs. low
0.38 0.22–0.68 0.001*
 Interferon signaling gene expression
 High vs. low
0.46 0.23–0.92 0.027*
  1. *Statistically significant