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Table 4 Table showing the change in the log-likelihood of the models with added prognostic terms. Statistical significance of the change was determined by a likelihood ratio test

From: Prognostic value of CD8 + PD-1+ immune infiltrates and PDCD1 gene expression in triple negative breast cancer

Variables DFS OS
∆LRχ2 P-value ∆LRχ2 P-value
CP +  PD-1 vs. CP 4.83 0.0280* 2.95 0.0856
CP +  PD-L1 vs. CP 5.22 0.0224* 3.95 0.0469*
CP +  CD274 vs. CP 3.66 0.0559 4.32 0.0378*
CP +  PDCD1 vs. CP 4.12 0.0425* 6.55 0.0105*
CP +  CD274  +  PDCD1 vs. CP 4.49 0.1057 6.12 0.0469*
CP +  PD-L1 + CD274 vs. CP 4.11 0.1278 7.02 0.0299*
CP +  PD-1+ + PDCD1 vs. CP 6.35 0.0417* 9.53 0.0085*
CP + CD8+PD-1+ vs. CP 7.53 0.0061* 3.16 0.0753
CP + IFNG vs. CP 7.50 0.0062* 5.29 0.0214*
  1. CP Clinicopathological parameters (patient age, tumor grade, tumor size and lymph node status), PD-1+ PD-1+ immune infiltrates (every 1 cell increment), PD-L1 PD-L1 tumor cell expression, LR Likelihood Ratio, CD8+PD-1+ CD8+PD-1+ T cells
  2. *Statistically significant