Fig. 3
From: Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients
Immunohistochemical assessment of Ki-67 positivity and CD8+ T cell infiltration. Representative fields for hematoxylin/eosin (a, d), CD8 positivity (b, e) and Ki-67 positivity (c, f) are depicted. The left hand panel (a-c) of a poorly proliferative tumor shows numerous CD8+ T-cells (c), while Ki-67 (b) stains very few neoplastic or immune cells. The right hand panel (d-f) of a highly proliferative tumor like the other case shows numerous CD8+ T-cells (f), while Ki-67 (e) stains a high number of neoplastic and immune cells. Scale bar = 100 μm