Fig. 5

Impact of PD-L1 levels and proliferative status on disease control rate in 110 NSCLC patients receiving an immune checkpoint inhibitor (ICI) as part of their therapy. a) Prevalence and DC rate for moderately versus highly and poorly proliferative tumors, as well as combined of the latter two. b) Prevalence and DC rate for strongly positive PD-L1 (TPS ≥ 50%). c) Prevalence and DC rate for PD-L1 negative (TPS < 1%). d) Prevalence and DC rate for strongly positive PD-L1 combined with moderately versus highly/poorly proliferative tumors. e) Prevalence and DC rate for PD-L1 positive (TPS ≥ 1%) combined with moderately versus highly/poorly proliferative tumors. f) Prevalence and DC rate for PD-L1 less than strongly positive (TPS < 50%) combined with moderately versus highly/poorly proliferative tumors. g) Prevalence and DC rate for PD-L1 negative (TPS < 1%) combined with moderately versus highly/poorly proliferative tumors. h) Prevalence and DC rate for weakly positive PD-L1 (TPS ≥ 1% and < 50%) combined with moderately versus highly/poorly proliferative tumors. i) Prevalence and DC rate for minimal tumor infiltration by CD8⁺ T cells (so-called “cold” tumors) combined with moderately versus highly/poorly proliferative tumors