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Table 2 Disease control for cell proliferation and PD-L1 IHC

From: Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients

Cell Proliferation PD-L1 IHC DC NDC Total pts DC rate χ2 test
Moderately   22 22 44 50.0%  
Highly 9 33 42 21.4% p = 0.0146
Poorly 4 20 24 16.7% p = 0.0113
Poorly/highly 13 53 66 19.7% p = 0.0017
  Strongly positive (TPS ≥ 50%) 16 16 32 50.0%  
Not strongly positive (TPS < 50%) 19 59 78 24.4% p = 0.0009
Positive (TPS ≥ 1%) 21 32 53 39.6%  
Negative (TPS < 1%) 14 43 57 24.6% p = 0.1363
Moderate Strongly positive (TPS ≥ 50%) 10 7 17 58.8%  
Poorly/highly 6 9 15 40.0% p = 0.4786
Moderately Not strongly positive (TPS < 50%) 12 15 27 44.4%  
Highly 4 25 29 13.8% p = 0.0250
Poorly 3 19 22 13.6% p = 0.0438
Poorly/highly 7 44 51 13.7% p = 0.0063
Moderately cold tumors (CD8 rank < 15%)   7 10 17 41.2%  
Poorly/highly cold tumors (CD8 rank < 15%) 7 33 40 17.5% p = 0.1179
Moderately cold tumors (CD8 rank < 33%)   5 5 10 50.0%  
Poorly/highly cold tumors (CD8 rank < 33%) 0 11 11 0.0% p = 0.3298