Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients

Table 3 Multivariate analysis

Variable		Estimate	Std. Error	z value	p value
(Intercept)		17.3526	2712.1561	0.006	0.9949
Proliferation Moderately		1.3503	0.5013	2.694	0.00707
PD.L1. status Positive		0.5169	0.547	0.945	0.34468
Histology SCC.or.Other		−0.5898	0.6417	−0.919	0.35801
race Black or African American		−34.8319	3301.0002	−0.011	0.99158
race Black or African American		−16.7776	2712.156	−0.006	0.99506
race Other		−35.6219	4796.5772	−0.007	0.99407
race Other		−34.6736	4796.5771	−0.007	0.99423
race Unknown		−18.5693	2712.1561	−0.007	0.99454
race White		−17.9126	2712.1559	−0.007	0.99473
race White		−18.3781	2712.1559	−0.007	0.99459
sex M		0.1522	0.5119	0.297	0.76616
age_cat 1–29		−35.0709	4796.5772	−0.007	0.99417
age_cat 40–49		−1.201	1.6759	−0.717	0.47359
age_cat 50–59		−0.6471	0.9129	−0.709	0.47843
age_cat 60–69		−0.9142	0.8863	−1.031	0.30233
age_cat 70–79		−1.1416	0.9098	−1.255	0.20955
Analysis of deviance of each co-variate
Co-variate	Df	Deviance	Resid. Df	Resid. Dev	P value(>Chi)
NULL			109	137.61
Proliferation	1	11.1163	108	126.49	0.0008557
PD.L1.status	1	4.5112	107	121.98	0.0336733
Histology	1	0.0593	106	121.92	0.8076295
race	7	7.4867	99	114.44	0.3800195
sex	1	0.1064	98	114.33	0.7442778
age_cat	5	4.2582	93	110.07	0.5128654