|
Cell line (Cell source)
|
% cytotoxicity (Mean ± SD) at different E:T ratios
|
E:T EC50
|
|---|
|
20:01
|
10:01
|
5:01
|
2.5:01
|
|---|
|
H2279 (ATCC)
|
97.22 ± 12.04
|
87.69 ± 11.65
|
47.69 ± 19.34
|
23.83 ± 13.53
|
4.03
|
|
H460 (ATCC)
|
89.27 ± 7.23
|
61.52 ± 8.30
|
30.09 ± 12.88
|
14.88 ± 8.75
|
4.86
|
|
12 (PDX)
|
83.43 ± 17.97
|
75.32 ± 18.10
|
50.66 ± 21.09
|
24.15 ± 10.97
|
5.76
|
|
178 (PDX)
|
83.03 ± 10.55
|
58.96 ± 12.30
|
34.43 ± 7.49
|
11.81 ± 2.83
|
6.7
|
|
426 (PDX)
|
83.00 ± 10.50
|
64.54 ± 13.74
|
40.79 ± 7.24
|
16.32 ± 4.46
|
7.47
|
|
277 (PDX)
|
81.25 ± 9.27
|
67.62 ± 14.95
|
47.25 ± 8.07
|
21.76 ± 6.73
|
7.56
|
|
655 (PDX)
|
81.14 ± 7.99
|
63.21 ± 8.85
|
31.84 ± 1.90
|
17.79 ± 1.77
|
7.97
|
|
229 (PDX)
|
80.64 ± 10.41
|
58.96 ± 10.73
|
27.98 ± 14.16
|
10.28 ± 5.43
|
8.86
|
|
H125 (ATCC)
|
78.62 ± 14.80
|
53.97 ± 19.28
|
24.05 ± 10.39
|
16.39 ± 8.94
|
9.53
|
|
239 (PDX)
|
63.57 ± 9.98
|
36.19 ± 16.83
|
11.82 ± 8.76
|
12.45 ± 3.81
|
16.8
|
|
A549 (ATCC)
|
60.12 ± 10.51
|
35.69 ± 5.41
|
18.28 ± 5.21
|
9.77 ± 4.50
|
16.93
|
|
137 (PDX)
|
53.66 ± 15.40
|
30.84 ± 13.30
|
16.67 ± 6.47
|
8.51 ± 2.90
|
20.57
|
- Primary and established human NSCLC cell lines were cocultured with ex vivo expanded DNTs at various E:T ratios. The percentages of specific cytotoxicity against target cells were detected. E:T EC50 was calculated for each cell line
