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Table 2 Summary table of results from viral infectivity assay

From: A phase 1 dose escalation study of the oncolytic adenovirus enadenotucirev, administered intravenously to patients with epithelial solid tumors (EVOLVE)

Time point Negative,a
n (%)
Positive,a n (%) Total number of patient samples analyzed
  Cells stain positive for virus Plaques in monolayer Complete/ partial monolayer destruction or quantifiable
Cycle 1, day 1 (day 0) 0 (0) 0 0 14 (100) 14
Cycle 2, day 1 (day 22) 3 (20) 0 4 (26.7) 8 (53.3) 15
Cycle 3, day 1 (day 43) 9 (75) 3 (25) 0 0 12
  1. aExample images for each level of infectivity are provided in Additional file 2: Figure S5