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Table 3 Sensitivity and positive predictive value with different tumor size change cut-offs

From: Are tumor size changes predictive of survival for checkpoint blockade based immunotherapy in metastatic melanoma?

Survive Additional t (years) from Week 12 + 20% −10% −30%
Sensitivity PPV Sensitivitya PPVb Sensitivity PPV
1 92.7% 82.6% 65.4% 87.1% 48.6% 91.0%
2 93.8% 66.2% 71.2% 75.6% 55.3% 82.8%
3 94.9% 57.6% 76.0% 69.1% 60.8% 77.7%
  1. aSensitivity: Prob (tumor size change “<= −10%” at Week 12 given surviving additional t years)
  2. bPositive Predictive Value (PPV): Prob(survive additional t years given tumor size change “<= − 10%” at Week 12)