1
|
Responders
|
f, 35
|
n.a.4
|
SSM5
|
mut
|
anti-PD19 + anti-CTLA410
|
4
|
Soft tissue, Lung, Liver, Spleen
|
PR
|
2
|
m, 93
|
2
|
SSM
|
wt
|
anti-PD1
|
2
|
Lymph nodes, Lung
|
SD*
|
3
|
f, 49
|
2
|
SSM
|
mut
|
anti-PD1 + anti-CTLA4
|
4
|
Lung, Liver, Lymph nodes, Brain
|
PR
|
4
|
f, 43
|
3
|
SSM
|
wt
|
anti-PD1
|
4
|
Lung, Lymph nodes, Soft tissue, Brain
|
PR
|
5
|
f, 54
|
2
|
SSM
|
mut
|
anti-PD1
|
2
|
Soft tissue, Lymph nodes
|
PR
|
6
|
m, 48
|
n.a.
|
nodular
|
wt
|
anti-PD1
|
3
|
Lymph nodes, Soft tissue, Bone
|
PR
|
7
|
m, 57
|
2
|
nodular
|
wt
|
anti-PD1
|
7
|
Soft tissue, Lymph nodes, Kidney, Peritoneum, Lung, Bone, Brain
|
SD*
|
8
|
f, 53
|
2
|
nodular
|
mut
|
anti-PD1
|
1
|
Lung
|
SD*
|
9
|
m, 36
|
2
|
nodular
|
wt
|
anti-PD1
|
2
|
Lung, Lymph nodes
|
PR
|
10
|
m, 75
|
n.a.
|
nodular
|
wt
|
anti-PD1
|
1
|
Lung
|
PR
|
11
|
m, 69
|
2
|
nodular
|
wt
|
anti-PD1
|
1
|
Soft tissue
|
PR
|
12
|
f, 49
|
2
|
nodular
|
wt
|
anti-PD1
|
1
|
Lung
|
PR
|
13
|
m, 30
|
4
|
nodular
|
mut
|
anti-PD1
|
1
|
Brain
|
PR
|
14
|
m, 65
|
2
|
naevoid
|
mut
|
anti-PD1 + anti-CTLA4
|
4
|
Soft tissue, Lung, Lymph nodes, Brain
|
PR
|
15
|
Non-Responders
|
m, 79
|
2
|
LMM6
|
wt
|
anti-PD1
|
2
|
Lymph nodes, Liver
|
SD*
|
16
|
f, 52
|
2
|
SSM
|
mut
|
anti-CTLA4
|
5
|
Soft tissue, Lung, Liver, Mesenterium, Brain
|
PD
|
17
|
m, 68
|
2
|
SSM
|
wt
|
anti-PD1
|
8
|
Soft tissue, Lymph nodes, Lung, Suprarenal gland, Liver, Intestinum, Bone, Brain
|
PD
|
18
|
f, 58
|
3
|
nodular
|
mut
|
anti-PD1
|
1
|
Brain
|
PD
|
19
|
m, 85
|
3
|
nodular
|
wt
|
anti-PD1
|
1
|
Brain
|
PD
|
20
|
m, 60
|
3
|
nodular
|
wt
|
anti-PD1 + anti-CTLA4
|
3
|
Lymph nodes, Lung, Liver
|
PD
|
21
|
m, 75
|
n.a.
|
desmoplastic
|
wt
|
anti-PD1
|
2
|
Lymph nodes, Liver
|
PD
|