Skip to main content

Table 1 Clinical and pathological characteristics of the study population

From: Efficacy of PD-1 blockade in cervical cancer is related to a CD8+FoxP3+CD25+ T-cell subset with operational effector functions despite high immune checkpoint levels

Clinical characteristics LN- (n = 14) LN+ (n = 13) PT (n = 10)
Age, mean ± SD 42,7 ± 9,5 47,6 ± 16,4 41,9 ± 12,1
FIGO stage
 IB1 6 (42) 2 (15) 7 (70)
 IB2 3 (22) 2 (15) 2 (20)
 IIA2 1 (7) 1 (8) 1 (10)
 IIB 3 (22) 6 (47) 0
 IIIB 1 (7) 2 (15) 0
Histology
 SCC 13 (93) 11 (85) 10 (100)
 ASCC 1 (7) 2a (15) 0
Vaginal involvement
 Yes 0 2 (15) 1 (10)
 No 11 (79) 10 (77) 9 (90)
 Unknown 3 (21) 1 (8) 0
Parametrium invasion
 Yes 6 (43) 10 (77) 0
 No 7 (50) 3 (23) 10 (100)
 Unknown 1 (7) 0 0
HPV-type
 6 0 1 (8) 0
 16 7 (50) 7 (53) 5 (50)
 18 1 (7) 2 (15) 0
 31 1 (7) 0 0
 33 0 1 (8) 1 (10)
 59 0 0 1 (10)
 Unknown 4 (29) 1 (8) 2 (20)
 p16+ 1 (7) 1 (10)
 Negative 0 1 (8) 0
  1. Values in the table expressed as n (%) a Two tumor-positive lymph nodes were collected from the same patient. Abbreviations: LN- tumor-negative lymph nodes, LN+ tumor-positive lymph node, FIGO International Federation of Gynecology and Obstetrics, SCC squamous cell carcinoma, ASCC adenosquamous cell carcinoma, HPV human papillomavirus, PT primary tumor