Table 6 Cox proportional-hazards regression: univariate and multivariate analyses according to non-overweight (< 25), overweight (25-30) and obese (≥ 30) BMI levels
Univariate Analysis | Multivariate Analysis | |
|---|---|---|
VARIABLE (Comparator) | HR (95% CI); p - value | HR (95% CI); p - value |
BMI (< 25) | Time to Treatment Failure | |
25–30 ≥ 30 | 0.49 (0.41–0.58); p < 0.0001 0.60 (0.47–0.77); p = 0.0001 | 0.67 (0.53–0.84); p = 0.0008 0.86 (0.61–1.24); p = 0.4414 |
BMI (< 25) | Progression Free Survival | |
25–30 ≥ 30 | 0.46 (0.39–0.55); p < 0.0001 0.46 (0.35–0.61); p < 0.0001 | 0.71 (0.56–0.89); p = 0.0044 0.80 (0.55–1.17); p = 0.2669 |
BMI (< 25) | Overall Survival | |
25–30 ≥ 30 | 0.33 (0.27–0.41); p < 0.0001 0.34 (0.25–0.48); p < 0.0001 | 0.49 (0.37–0.64); p < 0.0001 0.61 (0.39–0.94); p = 0.0258 |