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Fig. 7 | Journal for ImmunoTherapy of Cancer

Fig. 7

From: Interleukin-1 alpha increases anti-tumor efficacy of cetuximab in head and neck squamous cell carcinoma

Fig. 7

High serum IL-1α predicts progression free survival (PFS) in HNSCC patients treated with cetuximab-containing therapy. Baseline serum samples from 11 recurrent and/or metastatic (R/M) HNSCC patients scheduled for cetuximab-based chemotherapy (i.e. carboplatin, cisplatin, 5-FU, paclitaxel) at the University of Iowa Hospitals and Clinics Holden Comprehensive Cancer Center were collected. Serum IL-1α levels were measured by ELISA and patients were divided into two groups: detectable (n = 5) and undetectable (n = 6) IL-1α levels. Kaplan Meier survival curves were plotted for PFS for both groups. HR: hazard ratio; CI: confidence interval

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