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Fig. 1 | Journal for ImmunoTherapy of Cancer

Fig. 1

From: Use of targeted next generation sequencing to characterize tumor mutational burden and efficacy of immune checkpoint inhibition in small cell lung cancer

Fig. 1

a Tumor mutational burden (TMB) in patients who had a partial response (PR), stable disease (SD), or primary progressive disease (PD). Box plots represent medians, interquartile ranges, and vertical lines extend to the highest and the lowest TMB values. TMB of individual patients are represented with dots. b Proportion of patients with PR and SD in the TMB high versus TMB low groups (c) Waterfall plot showing the change (%) of tumor burden compared to baseline in patients with evaluable target lesions (N = 31). Among non-evaluable patients, 17 had clinical progression and died before scans while 4 had non measurable disease. One patient (indicated with an asterisk) had progressive disease in a non-target lesion

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