Fig. 8

STING agonist stimulates T cell chemokine expression. Conditioned medium from KPC1242 cells that had been stimulated with GEM alone, 10 μg/mL GEM plus 100 μg/mL DMXAA, DMXAA alone, or vehicle as a control were analyzed by MultiPlex or ELISA. Cytokine a and chemokine (b) levels in conditioned medium from treated and control cells. Data are triplicate means from a representative of 3 independent analyses. c, d CXCL10 and CCL20 chemokine levels measured by ELISA. Data are mean ± SD, n = 4 biological replicates completed in triplicate. ****, P ≤ 0.0001