- aStage IV melanoma patients or irresectable stage III melanoma patients
- bAnticipated capture of tumor antigens and maturation in vivo
- cmDC vaccination in combination with T-VEC intratumorally or anti-CTLA4 and anti-PDL1 intratumorally and anti-PD1 intravenously
- dAll mDCs obtained from the leukapheresis are injected
- Abbreviations: FSME, Frühsommer-meningoencephalitis; GM-CSF, granulocyte-macrophage colony-stimulating factor; mDC, myeloid dendritic cell; pDC, plasmacytoid dendritic cell; T-VEC, Talimogene laherparepvec. (source: clinicaltrials.gov and anzctr.org.au)