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Fig. 2 | Journal for ImmunoTherapy of Cancer

Fig. 2

From: The correlations of tumor mutational burden among single-region tissue, multi-region tissues and blood in non-small cell lung cancer

Fig. 2

tTMB fold-change based on multi-regions compared with single region. a For overall patients. For overall analysis, tTMB fold-change is computed by the mean tTMB of two-regions, three-regions, four-regions, five-regions, six-regions, seven-regions or eight-regions through a random iterated algorithm, then divided by that of the single region. b For different NSCLC subtypes. For subgroup analysis, tTMB fold-change is computed by the mean tTMB of two-regions or three-regions through a random iterated algorithm, then divided by that of the single region, because it shows insignificant tTMB fold-change increase if the included regions’ number more than three. Abbreviations: TMB, tumor mutational burden; tTMB, tissue TMB

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