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Fig. 3 | Journal for ImmunoTherapy of Cancer

Fig. 3

From: Automated image analysis of NSCLC biopsies to predict response to anti-PD-L1 therapy

Fig. 3

Predictive versus prognostic values of the CD8xPD-L1 signature. These are demonstrated by Kaplan-Meier analysis of overall survival for the CD8xPD-L1 signature in the combined (training and test) set of patients treated with durvalumab (a) compared to the set of non-immune checkpoint therapy (ICT) patients (b). Kaplan-Meier curves show survival probability, with shaded areas representing 95% confidence intervals. The prevalence for the non-ICT patients was matched to that for patients treated with durvalumab. The resulting cutoffs for CD8xPD-L1 signature positivity for the durvalumab and non-ICT sets respectively were 1.54 × 105 and 2.85 × 104 cells2/mm4

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