Feature name | Description | Notes |
---|---|---|
Expression level | The average expression level by cell line in melanoma tissue | |
Size difference | The absolute difference in size between the W.T. amino acid and the mutant | By Dalton units |
Hydrophobicity | The absolute difference in hydrophobicity index between the W.T. amino acid and the mutant | Kyte J, Doolittle RF |
Charge difference | The absolute difference in charge between the W.T. amino acid and the mutant | Values at ph = 7.4 |
Polar change | Categorical variable for the polarity change between the W.T. amino acid the mutant | Values at ph = 7.4 |
Cleavage score | Estimated cleavage probability of a full peptide. | Vider et al. |
Tap score | Estimated TAP binding energy | Peters et al. |