Skip to main content

Table 2 First column is the score name, second column is the description of the score

From: Level of neo-epitope predecessor and mutation type determine T cell activation of MHC binding peptides

Feature name Description Notes
Expression level The average expression level by cell line in melanoma tissue http://www.ebi.ac.uk/
Size difference The absolute difference in size between the W.T. amino acid and the mutant By Dalton units
Hydrophobicity The absolute difference in hydrophobicity index between the W.T. amino acid and the mutant Kyte J, Doolittle RF
Charge difference The absolute difference in charge between the W.T. amino acid and the mutant Values at ph = 7.4
Polar change Categorical variable for the polarity change between the W.T. amino acid the mutant Values at ph = 7.4
Cleavage score Estimated cleavage probability of a full peptide. Vider et al.
Tap score Estimated TAP binding energy Peters et al.
  1. Third column is a description of the score and the reference for the score