|
Patients (N = 20)
|
---|
ONC201 (mg)
|
375
|
625
|
---|
No. of Patients (%)
|
3 (15%)
|
17 (85%)
|
Male
|
2
|
8
|
Female
|
1
|
9
|
ECOG
|
ECOG = 0
|
2 (10%)
|
6 (30%)
|
ECOG = 1
|
1 (5%)
|
11 (55%)
|
Age (years)a
|
80 (42–92)
|
64 (35–79)
|
Weight (kg)a
|
51.3 (50.4–55.0)
|
82.7 (56.4–109.1)
|
Dosesa
|
21 (18–30)
|
19.6 (4–70)
|
Prior Therapies
|
Prior hormonal therapiesa
|
0
|
1.2 (1–6)
|
Prior chemotherapiesa
|
2.3 (0–4)
|
2.2 (0–7)
|
Prior immunotherapiesa
|
1 (0–2)
|
0.2 (0–1)
|
Prior targeted therapiesa
|
0.7 (0–2)
|
0.8 (0–4)
|
Prior Radiationa
|
1.5 (1–2)
|
1 (1–3)
|
Prior Surgerya
|
2 (2–3)
|
3 (1–7)
|
- a Indicates that the datum is reported as the mean with the range in parentheses