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Table 1 Demographics and clinical characteristics of patients treated with ONC201 who were evaluable for safety and efficacy

From: Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration

 

Patients (N = 20)

ONC201 (mg)

375

625

No. of Patients (%)

3 (15%)

17 (85%)

Male

2

8

Female

1

9

ECOG

 ECOG = 0

2 (10%)

6 (30%)

 ECOG = 1

1 (5%)

11 (55%)

Age (years)a

80 (42–92)

64 (35–79)

Weight (kg)a

51.3 (50.4–55.0)

82.7 (56.4–109.1)

Dosesa

21 (18–30)

19.6 (4–70)

Prior Therapies

 Prior hormonal therapiesa

0

1.2 (1–6)

 Prior chemotherapiesa

2.3 (0–4)

2.2 (0–7)

 Prior immunotherapiesa

1 (0–2)

0.2 (0–1)

 Prior targeted therapiesa

0.7 (0–2)

0.8 (0–4)

Prior Radiationa

1.5 (1–2)

1 (1–3)

Prior Surgerya

2 (2–3)

3 (1–7)

  1. a Indicates that the datum is reported as the mean with the range in parentheses