| Patients (N = 20) | |
---|---|---|
ONC201 (mg) | 375 | 625 |
No. of Patients (%) | 3 (15%) | 17 (85%) |
Male | 2 | 8 |
Female | 1 | 9 |
ECOG | ||
 ECOG = 0 | 2 (10%) | 6 (30%) |
 ECOG = 1 | 1 (5%) | 11 (55%) |
Age (years)a | 80 (42–92) | 64 (35–79) |
Weight (kg)a | 51.3 (50.4–55.0) | 82.7 (56.4–109.1) |
Dosesa | 21 (18–30) | 19.6 (4–70) |
Prior Therapies | ||
 Prior hormonal therapiesa | 0 | 1.2 (1–6) |
 Prior chemotherapiesa | 2.3 (0–4) | 2.2 (0–7) |
 Prior immunotherapiesa | 1 (0–2) | 0.2 (0–1) |
 Prior targeted therapiesa | 0.7 (0–2) | 0.8 (0–4) |
Prior Radiationa | 1.5 (1–2) | 1 (1–3) |
Prior Surgerya | 2 (2–3) | 3 (1–7) |