|
Patient
|
Age (Years)
|
Sex
|
HPV type
|
Age at diagnosis (Years)
|
Number of RRP surgeries lifetime
|
Prior local treatments
|
Prior systemic treatments
|
Pulmonary RRP lesions
|
|---|
|
1
|
32
|
F
|
11
|
19
|
> 40
|
Cidofovir
|
I-3-C
|
No
|
|
2
|
36
|
M
|
6
|
28
|
35
|
Cidovofir, bevacizumab
|
I-3-C
|
No
|
|
3
|
50
|
F
|
11
|
5
|
> 250
|
Mitomycin
|
Diindolylmethane
|
Yes
|
|
4
|
63
|
M
|
11
|
19
|
> 50
|
Cidofovir, Cryotherapy
|
None
|
No
|
|
5
|
27
|
F
|
6
|
6
|
> 50
|
None
|
None
|
No
|
|
6
|
53
|
F
|
11
|
38
|
> 20
|
Cidofovir
|
None
|
Yes
|
|
7
|
55
|
M
|
6
|
53
|
11
|
Cidovofir, bevacizumab
|
None
|
No
|
|
8
|
55
|
F
|
6
|
51
|
16
|
None
|
None
|
No
|
|
9
|
56
|
M
|
11
|
54
|
> 20
|
Cidofovir
|
None
|
No
|
|
10
|
21
|
M
|
6
|
1
|
> 100
|
Cidovofir, bevacizumab
|
Interferon, Methotrexate
|
Yes
|
|
11
|
67
|
M
|
6
|
28
|
> 40
|
bevacizumab, PDT
|
I-3-C
|
Yes
|
|
12
|
26
|
M
|
11
|
2
|
> 100
|
Cidofovir, bevacizumab
|
Interferon, I-3-C
|
No
|
- Abbreviations: HPV human papillomavirus, RRP recurrent respiratory papillomatosis, PDT photodynamic therapy, I-3-C indole-3-carbinol
