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Fig. 3 | Journal for ImmunoTherapy of Cancer

Fig. 3

From: Selectively hampered activation of lymph node-resident dendritic cells precedes profound T cell suppression and metastatic spread in the breast cancer sentinel lymph node

Fig. 3

T-cell subsets and activation. Frequencies of (a) CD4+ and CD8+ T-cells in HLN, metastasis negative (SLN-) and metastasis positive (SLN+) breast cancer SLN. b Expression of activation (HLA-DR; ICOS) and checkpoint (CLTA-4; PD-1) molecules on CD4+ T-cells (left graph) and CD8+ T-cells (right graph). Bars represent mean +/− SEM. * p = 0.01 to 0.05; ** p = 0.001 to 0.01; *** p = 0.001 to 0.0001 in a one way ANOVA or Kruskal-Wallis with post-hoc multiple comparison Tukey’s or Dunn’s test

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