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Fig. 4 | Journal for ImmunoTherapy of Cancer

Fig. 4

From: Selectively hampered activation of lymph node-resident dendritic cells precedes profound T cell suppression and metastatic spread in the breast cancer sentinel lymph node

Fig. 4

DC and T cell cytokine profiles. Cytokine release by single cell suspensions from HLN (N = 3), SLN- (N = 3) and SLN+ (N = 3) upon (a) DC specific stimulation with R848 and (b) T-cell specific stimulation with plate bound CD3/CD28 antibodies. Bars represent mean +/− SEM. * p = 0.01 to 0.05; *** p = 0.0001 to 0.001 and **** p < 0.0001 in a one way ANOVA with post-hoc multiple comparison Tukey’s test

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