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Fig. 5 | Journal for ImmunoTherapy of Cancer

Fig. 5

From: Selectively hampered activation of lymph node-resident dendritic cells precedes profound T cell suppression and metastatic spread in the breast cancer sentinel lymph node

Fig. 5

Frequencies and expression of surface molecules of DC subsets in relation to BrC subtype. a Frequencies and (b) expression of activation/maturation (CD40, CD83) and co-stimulatory (CD86) surface receptors (horizontal columns) of migratory DC subsets (left vertical column) and LN resident DC susets (right vertical column) in BrC SLN. In each graph the left scatterplots represent all ER+ and/or PR+ (HR+) tumors and the right scatterplots all Triple Negative or HER2+/ER and PR- (HR-) tumors. Bars represent mean +/− SEM. * p = 0.01 to 0.05; ** p = 0.001 to 0.01; in an unpaired (two-tailed) T test or Mann-Whitney test

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