Selectively hampered activation of lymph node-resident dendritic cells precedes profound T cell suppression and metastatic spread in the breast cancer sentinel lymph node

Table 1 Clinical and pathological characteristics

Clinical and pathological characteristics	HLN (N = 17)	SLN- (N = 44)	SLN+ (N = 14)	p-value
Age (mean ± SD)	38.7 ± 11.8	59.1 ± 10.2	52.9 ± 12.9	0.07 ^A
Primary tumor size (cm)		1.41 ± 0.69	2.67 ± 2.08	0.002 ^A
T stage				<0.01 ^B
T1 (< 2 cm)		38	6
T2 (≥ 2–5 cm)		6	7
≥T3 (> 5 cm)		0	1
Histology				0.72 ^B
Ductal		35	12
Lobular		4	1
Mixed ductal/lobular		3	0
Papillary		1	0
Mucinous		1	1
Differentiation grade				0.35 ^B
1		10	3
2		22	6
3		12	4
Unknown		0	1
ER expression				0.39 ^C
Yes		39	11
No		5	3
PR expression				1.00 ^C
Yes		35	11
No		9	3
HER2 amplification				1.00 ^C
Yes		8	3
No		36	11
Breast cancer subtype				0.45 ^B
HR positive (ER+ and/or PR+)		39	11
HER2+		4	1
TNBC		2	2

^Aby two-sided unpaired t-test; ^B by Pearson chi-square test; ^C by Fisher’s exact test