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Fig. 1 | Journal for ImmunoTherapy of Cancer

Fig. 1

From: PD-L1 detection using 89Zr-atezolizumab immuno-PET in renal cell carcinoma tumorgrafts from a patient with favorable nivolumab response

Fig. 1

Clinical case. a Coronal contrast-enhanced CT images of a lytic metastasis in the left 10th rib (red arrow) before and after SABR and HD-IL2. b Axial contrast-enhanced CT image of new lytic metastasis in the right distal anterolateral femur (red arrow), which developed after SABR/HD-IL2 therapy. c Coronal proton density fat saturated MR imaging of an osseous metastasis in right glenoid (red arrow) that developed while on pazopanib therapy. d Clinical images illustrating radiation recall dermatitis 11 days after first nivolumab infusion at two prior sites of radiation, the left rib (A, radiated six months prior) and the right knee (B, radiated one month prior). Outlined is an area of subcutaneous edema and discoloration (C) attributed to drainage from lesion A. e Axial contrast-enhanced CT scan of the chest of representative lingular nodule (red arrow) improving with nivolumab therapy. f Hematoxylin and eosin stains of left colon biopsy with increased intraepithelial lymphocytes and cryptitis representative of autoimmune colitis

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