Fig. 2

Tumorgraft immunoPET studies. a Patient’s tumor (nephrectomy sample) and corresponding tumorgraft demonstrating sarcomatoid differentiation and high PD-L1 expression by IHC. b iPET from representative NOD/SCID mouse with subcutaneous tumorgraft. c-d Images (patient and tumorgraft) from papillary RCC tumor chosen as a control because of low PD-L1 levels. Tumor volumes shown for the individual mice are estimated based on the CT volume quantification of the tumors