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Fig. 6 | Journal for ImmunoTherapy of Cancer

Fig. 6

From: Targeting of M2-like tumor-associated macrophages with a melittin-based pro-apoptotic peptide

Fig. 6

Selective cell death of M2-like TAMs by MEL-dKLA in the tumor stroma. (a) The representative histograms of Annexin+ cells in F4/80+CD86+ M1 macrophages or (b) F4/80+CD206+ M2 macrophages were normalized to maximum peak and displayed as half offset histograms. (c) The percentages of Annexin V+ cells in M1 or M2 macrophages are shown in a bar graph. **P < 0.01 versus the PBS group, ##P < 0.01 versus the dKLA group, $$P < 0.01 versus the MEL group, &&&P < 0.0001 versus the M1 group (n = 6)

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