Fig. 2
From: Gal9/Tim-3 expression level is higher in AML patients who fail chemotherapy
The increase of TIM-3 expression was higher in TF compare to CR patients. Median Fluorescence Intensity (MFI) was calculated by FlowJo-10 software and relative normalized to comparing TIM-3 expressing T cells (CD4+ and CD8+) and PDL-1+ CD34+ cells in CR and TF patients at time of diagnosis and end of induction (a-b). Comparison of PDL-1 expression on CD34+ AML cells in CR and TF patients. (c) The colored overlay dot plots show the co-expression of TIM-3 and PD-1 on CD4+ and CD8+ cells comparing expression levels of these receptors in representative patients CR (blue dot) and TF (red dot) at diagnosis vs end of induction (d)